the first cut is the deepest

I did get some rather fun answers this time around.  I'll have to do it again soon.

Rejection, loneliness....those were the major ones.  I don't see why.  Humans are incredibly resilient when it comes to hardships and there's no reason to think that it would change just because of a single person.  As for myself, I suppose I would be disappointed if Akabane-san or Rena-chan or perhaps even Kyon-kun or Koizumi Itsuki or Nagato managed to kill themselves in some manner.  They're too interesting to lose in such a short period of time.  I would miss their reactions.

.....Hm.  Maybe this is what they mean.